Industrial development relies on maintaining sustainable development, optimizing industrial structure and boosting industrial GTFP amid the current economic situation. This paper, according to industrial data in Jiangsu province, uses DEA model to measure their GTFP which is used to divide the industrial sector into 5 divisions, discusses the spatial overflow and its decomposition of industrial structure on GTFP from weights of adjacent space, geographic distance and economy distance. Jiangsu's GTFP is of highly spatial concentration, and of same orientation on inside and outside of region of each industrial department, with same symbols of direct and in-direct effects. Influences of controlling variables on GTFP vary. Industrial structure is of overflow effect among Jiangsu's regions, whose industrial structure still has highly energy-consuming, highly polluting, and highly emitting companies, impeding its economic transformation and upgrading to some extent, crucial to its successful kinetic transformation of industrial structure.